I60M (p.Ile60Met) variant of SLC8A1 (Sodium/calcium exchanger 1)
I60M (p.Ile60Met) in SLC8A1 (Sodium/calcium exchanger 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
I60M (p.Ile60Met) variant details
- p.Ile60Met
- ExAC rs761710337
- gnomAD rs761710337
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.22
- CADD 18.30
- PolyPhen-2 0.62
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available