A35T (p.Ala35Thr) variant of SLC8A1 (Sodium/calcium exchanger 1)
A35T (p.Ala35Thr) in SLC8A1 (Sodium/calcium exchanger 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A35T (p.Ala35Thr) variant details
- p.Ala35Thr
- gnomAD rs1353379967
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.14
- CADD 22.70
- PolyPhen-2 0.05
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available