W82C (p.Trp82Cys) variant of SLC6A4 (P31645)
W82C (p.Trp82Cys) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data and structural context.
W82C (p.Trp82Cys) variant details
- p.Trp82Cys
- TOPMed rs1906765696
- gnomAD rs1906765696
- Missense
- Variant Prioritization Score for Impact Estimate 0.903
- REVEL 0.93
- ESM-1b 1.00
- AlphaMissense 1.00
- MetaLR 0.89
- MetaSVM 1.04
- CADD 29.30
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available