T81A (p.Thr81Ala) variant of SLC6A4 (P31645)
T81A (p.Thr81Ala) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T81A (p.Thr81Ala) variant details
- p.Thr81Ala
- gnomAD rs1289152192
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.23
- ESM-1b 1.00
- AlphaMissense 0.14
- MetaLR 0.29
- MetaSVM -0.66
- CADD 23.30
- Most common in the HGDP:SAN population (allele frequency 0.25)
- Structural context available