T66S (p.Thr66Ser) variant of SLC6A4 (P31645)
T66S (p.Thr66Ser) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T66S (p.Thr66Ser) variant details
- p.Thr66Ser
- TOPMed rs1171155787
- gnomAD rs1171155787
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.16
- MetaSVM -1.01
- CADD 11.80
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available