T66P (p.Thr66Pro) variant of SLC6A4 (P31645)
T66P (p.Thr66Pro) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T66P (p.Thr66Pro) variant details
- p.Thr66Pro
- TOPMed rs1171155787
- gnomAD rs1171155787
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.11
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.12
- MetaSVM -1.01
- CADD 14.90
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available