T66A (p.Thr66Ala) variant of SLC6A4 (P31645)
T66A (p.Thr66Ala) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T66A (p.Thr66Ala) variant details
- p.Thr66Ala
- TOPMed rs1171155787
- gnomAD rs1171155787
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.05
- MetaLR 0.08
- MetaSVM -0.98
- CADD 10.50
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 1)
- Structural context available