T4M (p.Thr4Met) variant of SLC6A4 (P31645)
T4M (p.Thr4Met) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T4M (p.Thr4Met) variant details
- p.Thr4Met
- cosmic curated COSV55565
- ExAC rs201688297
- TOPMed rs201688297
- gnomAD rs201688297
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.26
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.22
- MetaSVM -0.86
- CADD 17.70
- Most common in the 1KG:MSL population (allele frequency 0.31)
- Structural context available