T4A (p.Thr4Ala) variant of SLC6A4 (P31645)
T4A (p.Thr4Ala) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
T4A (p.Thr4Ala) variant details
- p.Thr4Ala
- ExAC rs765035150
- TOPMed rs765035150
- gnomAD rs765035150
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.18
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.19
- MetaSVM -0.90
- CADD 16.10
- Most common in the 1KG:MSL population (allele frequency 0.31)
- Structural context available