T122I (p.Thr122Ile) variant of SLC6A4 (P31645)
T122I (p.Thr122Ile) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T122I (p.Thr122Ile) variant details
- p.Thr122Ile
- TOPMed rs1199374764
- gnomAD rs1199374764
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.13
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.14
- MetaSVM -0.95
- CADD 20.50
- Most common in the Non-Finnish European population (allele frequency 2.5e-05)
- Structural context available