T122A (p.Thr122Ala) variant of SLC6A4 (P31645)
T122A (p.Thr122Ala) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T122A (p.Thr122Ala) variant details
- p.Thr122Ala
- Ensembl rs2143015196
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.22
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.27
- MetaSVM -0.59
- CADD 21.20
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available