S62C (p.Ser62Cys) variant of SLC6A4 (P31645)
S62C (p.Ser62Cys) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
S62C (p.Ser62Cys) variant details
- p.Ser62Cys
- ExAC rs201041934
- TOPMed rs201041934
- gnomAD rs201041934
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.18
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.26
- MetaSVM -0.73
- CADD 19.70
- Most common in the REMAINING population (allele frequency 0.00015)
- Structural context available