S40F (p.Ser40Phe) variant of SLC6A4 (P31645)
S40F (p.Ser40Phe) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S40F (p.Ser40Phe) variant details
- p.Ser40Phe
- TOPMed rs1906772093
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.12
- MetaSVM -0.98
- CADD 16.20
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available