R79P (p.Arg79Pro) variant of SLC6A4 (P31645)
R79P (p.Arg79Pro) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
R79P (p.Arg79Pro) variant details
- p.Arg79Pro
- ExAC rs760517433
- TOPMed rs760517433
- gnomAD rs760517433
- Missense
- Variant Prioritization Score for Impact Estimate 0.791
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 0.34
- MetaLR 0.23
- MetaSVM -0.76
- CADD 27.70
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available