R60Q (p.Arg60Gln) variant of SLC6A4 (P31645)
R60Q (p.Arg60Gln) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
R60Q (p.Arg60Gln) variant details
- p.Arg60Gln
- ExAC rs748936504
- TOPMed rs748936504
- gnomAD rs748936504
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.04
- MetaSVM -1.04
- CADD 0.16
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.7e-05)
- Structural context available