R104H (p.Arg104His) variant of SLC6A4 (P31645)
R104H (p.Arg104His) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data and structural context.
R104H (p.Arg104His) variant details
- p.Arg104His
- Ensembl rs1906763538
- Missense
- Variant Prioritization Score for Impact Estimate 0.896
- REVEL 0.94
- ESM-1b 1.00
- AlphaMissense 0.86
- MetaLR 0.85
- MetaSVM 0.92
- CADD 27.60
- Most common in the HGDP:YORUBA population (allele frequency 0.21)
- Structural context available