Q42K (p.Gln42Lys) variant of SLC6A4 (P31645)
Q42K (p.Gln42Lys) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Q42K (p.Gln42Lys) variant details
- p.Gln42Lys
- cosmic curated COSV55565
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.18
- MetaSVM -0.94
- CADD 19.60
- Most common in the 1KG:MSL population (allele frequency 0.31)
- Structural context available