P106L (p.Pro106Leu) variant of SLC6A4 (P31645)
P106L (p.Pro106Leu) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data and structural context.
P106L (p.Pro106Leu) variant details
- p.Pro106Leu
- cosmic curated COSV10802
- gnomAD rs1207932786
- Missense
- Variant Prioritization Score for Impact Estimate 0.9
- REVEL 0.93
- ESM-1b 1.00
- AlphaMissense 0.98
- MetaLR 0.94
- MetaSVM 1.09
- CADD 28.00
- Most common in the 1KG:MSL population (allele frequency 0.19)
- Structural context available