N145S (p.Asn145Ser) variant of SLC6A4 (P31645)
N145S (p.Asn145Ser) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
N145S (p.Asn145Ser) variant details
- p.Asn145Ser
- ExAC rs770637680
- gnomAD rs770637680
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.14
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.14
- MetaSVM -0.99
- CADD 17.90
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available