M124T (p.Met124Thr) variant of SLC6A4 (P31645)
M124T (p.Met124Thr) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
M124T (p.Met124Thr) variant details
- p.Met124Thr
- ExAC rs779391253
- gnomAD rs779391253
- Missense
- Variant Prioritization Score for Impact Estimate 0.712
- REVEL 0.77
- ESM-1b 0.93
- AlphaMissense 0.58
- MetaLR 0.57
- MetaSVM 0.11
- CADD 26.40
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available