L90F (p.Leu90Phe) variant of SLC6A4 (P31645)
L90F (p.Leu90Phe) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
L90F (p.Leu90Phe) variant details
- p.Leu90Phe
- gnomAD rs1183088111
- Missense
- Variant Prioritization Score for Impact Estimate 0.711
- REVEL 0.77
- ESM-1b 1.00
- AlphaMissense 0.50
- MetaLR 0.73
- MetaSVM 0.56
- CADD 25.80
- Most common in the 1KG:MSL population (allele frequency 0.31)
- Structural context available