K85N (p.Lys85Asn) variant of SLC6A4 (P31645)
K85N (p.Lys85Asn) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
K85N (p.Lys85Asn) variant details
- p.Lys85Asn
- TOPMed rs1459089712
- gnomAD rs1459089712
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.68
- ESM-1b 1.00
- AlphaMissense 0.95
- MetaLR 0.29
- MetaSVM -0.45
- CADD 23.80
- Most common in the 1KG:MSL population (allele frequency 0.19)
- Structural context available