K85M (p.Lys85Met) variant of SLC6A4 (P31645)
K85M (p.Lys85Met) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
K85M (p.Lys85Met) variant details
- p.Lys85Met
- TOPMed rs1332783171
- gnomAD rs1332783171
- Missense
- Variant Prioritization Score for Impact Estimate 0.832
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 0.91
- MetaLR 0.80
- MetaSVM 0.88
- CADD 27.20
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available