K84E (p.Lys84Glu) variant of SLC6A4 (P31645)
K84E (p.Lys84Glu) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
K84E (p.Lys84Glu) variant details
- p.Lys84Glu
- ExAC rs748124693
- TOPMed rs748124693
- gnomAD rs748124693
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- REVEL 0.64
- ESM-1b 1.00
- AlphaMissense 0.32
- MetaLR 0.62
- MetaSVM 0.38
- CADD 27.70
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 1)
- Structural context available