K37I (p.Lys37Ile) variant of SLC6A4 (P31645)
K37I (p.Lys37Ile) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K37I (p.Lys37Ile) variant details
- p.Lys37Ile
- gnomAD rs1372689679
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.15
- MetaLR 0.15
- MetaSVM -0.97
- CADD 22.50
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 1)
- Structural context available