K159E (p.Lys159Glu) variant of SLC6A4 (P31645)
K159E (p.Lys159Glu) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
K159E (p.Lys159Glu) variant details
- p.Lys159Glu
- TOPMed rs1264232560
- gnomAD rs1264232560
- Missense
- Variant Prioritization Score for Impact Estimate 0.707
- REVEL 0.76
- ESM-1b 1.00
- AlphaMissense 0.69
- MetaLR 0.52
- MetaSVM 0.00
- CADD 29.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available