K153Q (p.Lys153Gln) variant of SLC6A4 (P31645)
K153Q (p.Lys153Gln) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
K153Q (p.Lys153Gln) variant details
- p.Lys153Gln
- TOPMed rs1176511049
- gnomAD rs1176511049
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.52
- ESM-1b 0.00
- AlphaMissense 0.16
- MetaLR 0.52
- MetaSVM 0.07
- CADD 28.30
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available