I63V (p.Ile63Val) variant of SLC6A4 (P31645)
I63V (p.Ile63Val) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I63V (p.Ile63Val) variant details
- p.Ile63Val
- TOPMed rs1362266683
- gnomAD rs1362266683
- Missense
- Variant Prioritization Score for Impact Estimate 0.0806
- REVEL 0.01
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.07
- MetaSVM -1.06
- CADD 0.15
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available