I63F (p.Ile63Phe) variant of SLC6A4 (P31645)
I63F (p.Ile63Phe) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I63F (p.Ile63Phe) variant details
- p.Ile63Phe
- TOPMed rs1362266683
- gnomAD rs1362266683
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.03
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.09
- MetaSVM -1.00
- CADD 6.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available