I161V (p.Ile161Val) variant of SLC6A4 (P31645)
I161V (p.Ile161Val) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
I161V (p.Ile161Val) variant details
- p.Ile161Val
- gnomAD rs1906644426
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.27
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.35
- MetaSVM -0.58
- CADD 22.60
- Most common in the 1KG:MSL population (allele frequency 0.19)
- Structural context available