I161T (p.Ile161Thr) variant of SLC6A4 (P31645)
I161T (p.Ile161Thr) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
I161T (p.Ile161Thr) variant details
- p.Ile161Thr
- ExAC rs201833332
- TOPMed rs201833332
- gnomAD rs201833332
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.85
- ESM-1b 0.81
- AlphaMissense 0.18
- MetaLR 0.63
- MetaSVM 0.35
- CADD 26.80
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.7e-05)
- Structural context available