I148V (p.Ile148Val) variant of SLC6A4 (P31645)
I148V (p.Ile148Val) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
I148V (p.Ile148Val) variant details
- p.Ile148Val
- gnomAD rs1167206964
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.37
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.42
- MetaSVM -0.33
- CADD 23.90
- Most common in the 1KG:MSL population (allele frequency 0.31)
- Structural context available