I126V (p.Ile126Val) variant of SLC6A4 (P31645)
I126V (p.Ile126Val) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I126V (p.Ile126Val) variant details
- p.Ile126Val
- ExAC rs755449138
- gnomAD rs755449138
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.12
- ESM-1b 0.00
- AlphaMissense 0.05
- MetaLR 0.14
- MetaSVM -1.06
- CADD 7.41
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available