G41R (p.Gly41Arg) variant of SLC6A4 (P31645)
G41R (p.Gly41Arg) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G41R (p.Gly41Arg) variant details
- p.Gly41Arg
- ESP rs140436169
- ExAC rs140436169
- TOPMed rs140436169
- gnomAD rs140436169
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.25
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.26
- MetaSVM -0.71
- CADD 7.64
- Most common in the HGDP:PAPUANSEPIK population (allele frequency 1)
- Structural context available