G35R (p.Gly35Arg) variant of SLC6A4 (P31645)
G35R (p.Gly35Arg) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G35R (p.Gly35Arg) variant details
- p.Gly35Arg
- ExAC rs754684306
- gnomAD rs754684306
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.18
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.33
- MetaSVM -0.59
- CADD 15.20
- Most common in the 1KG:MSL population (allele frequency 0.19)
- Structural context available