G35E (p.Gly35Glu) variant of SLC6A4 (P31645)
G35E (p.Gly35Glu) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
G35E (p.Gly35Glu) variant details
- p.Gly35Glu
- ESP rs372056901
- ExAC rs372056901
- gnomAD rs372056901
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.14
- MetaSVM -1.00
- CADD 0.88
- Most common in the African/African-American population (allele frequency 9.7e-05)
- Structural context available