D87Y (p.Asp87Tyr) variant of SLC6A4 (P31645)
D87Y (p.Asp87Tyr) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data and structural context.
D87Y (p.Asp87Tyr) variant details
- p.Asp87Tyr
- TOPMed rs1159379145
- gnomAD rs1159379145
- Missense
- Variant Prioritization Score for Impact Estimate 0.867
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 0.92
- MetaLR 0.72
- MetaSVM 0.68
- CADD 26.50
- Most common in the HGDP:SAN population (allele frequency 1)
- Structural context available