C15S (p.Cys15Ser) variant of SLC6A4 (P31645)
C15S (p.Cys15Ser) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
C15S (p.Cys15Ser) variant details
- p.Cys15Ser
- cosmic curated COSV55570
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.23
- MetaSVM -0.94
- CADD 0.65
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.55)
- Structural context available