A138T (p.Ala138Thr) variant of SLC6A4 (P31645)
A138T (p.Ala138Thr) in SLC6A4 (P31645) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
A138T (p.Ala138Thr) variant details
- p.Ala138Thr
- ExAC rs201802369
- TOPMed rs201802369
- gnomAD rs201802369
- Missense
- Variant Prioritization Score for Impact Estimate 0.772
- REVEL 0.80
- ESM-1b 1.00
- AlphaMissense 0.26
- MetaLR 0.61
- MetaSVM 0.29
- CADD 26.00
- Most common in the HGDP:PAPUANSEPIK population (allele frequency 1)
- Structural context available