P26R (p.Pro26Arg) variant of SLC6A3 (Q01959)
P26R (p.Pro26Arg) in SLC6A3 (Q01959) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P26R (p.Pro26Arg) variant details
- p.Pro26Arg
- ExAC rs757417973
- TOPMed rs757417973
- gnomAD rs757417973
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.13
- MetaLR 0.25
- MetaSVM -0.84
- CADD 15.60
- PolyPhen-2 0.04
- SIFT 0.10
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available