L10F (p.Leu10Phe) variant of SLC6A3 (Q01959)
L10F (p.Leu10Phe) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- TOPMed rs1364589480
- gnomAD rs1364589480
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.15
- AlphaMissense 0.07
- MetaLR 0.10
- MetaSVM -0.99
- CADD 13.70
- PolyPhen-2 0.00
- Most common in the East Asian population (allele frequency 0.00038)
- Structural context available