K65R (p.Lys65Arg) variant of SLC6A3 (Q01959)
K65R (p.Lys65Arg) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
K65R (p.Lys65Arg) variant details
- p.Lys65Arg
- TOPMed rs1196361940
- gnomAD rs1196361940
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.28
- MetaLR 0.29
- MetaSVM -0.69
- CADD 23.00
- PolyPhen-2 0.07
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available