I67F (p.Ile67Phe) variant of SLC6A3 (Q01959)
I67F (p.Ile67Phe) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
I67F (p.Ile67Phe) variant details
- p.Ile67Phe
- gnomAD rs1733717269
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.49
- MetaLR 0.41
- MetaSVM -0.52
- CADD 23.40
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available