G39R (p.Gly39Arg) variant of SLC6A3 (Q01959)
G39R (p.Gly39Arg) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G39R (p.Gly39Arg) variant details
- p.Gly39Arg
- TOPMed rs1560897827
- gnomAD rs1560897827
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- REVEL 0.52
- MetaLR 0.55
- MetaSVM 0.17
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available