G25D (p.Gly25Asp) variant of SLC6A3 (Q01959)
G25D (p.Gly25Asp) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- gnomAD rs1329405298
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.17
- MetaLR 0.31
- MetaSVM -0.61
- CADD 18.30
- PolyPhen-2 0.01
- SIFT 0.30
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available