D68Y (p.Asp68Tyr) variant of SLC6A3 (Q01959)
D68Y (p.Asp68Tyr) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
D68Y (p.Asp68Tyr) variant details
- p.Asp68Tyr
- 1000Genomes rs527940312
- TOPMed rs527940312
- Missense
- Variant Prioritization Score for Impact Estimate 0.802
- REVEL 0.85
- MetaLR 0.71
- MetaSVM 0.70
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available