D59H (p.Asp59His) variant of SLC6A3 (Q01959)
D59H (p.Asp59His) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D59H (p.Asp59His) variant details
- p.Asp59His
- TOPMed rs1469449884
- gnomAD rs1469449884
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.14
- MetaLR 0.19
- MetaSVM -0.77
- CADD 16.60
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available