C6Y (p.Cys6Tyr) variant of SLC6A3 (Q01959)
C6Y (p.Cys6Tyr) in SLC6A3 (Q01959) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
C6Y (p.Cys6Tyr) variant details
- p.Cys6Tyr
- ExAC rs746803347
- TOPMed rs746803347
- gnomAD rs746803347
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.11
- MetaLR 0.23
- MetaSVM -0.88
- CADD 20.50
- PolyPhen-2 0.33
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available