W65R (p.Trp65Arg) variant of SLC5A2 (Sodium/glucose cotransporter 2)
W65R (p.Trp65Arg) in SLC5A2 (Sodium/glucose cotransporter 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
W65R (p.Trp65Arg) variant details
- p.Trp65Arg
- gnomAD 16-31484739-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.729
- REVEL 0.79
- CADD 27.20
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available