R167K (p.Arg167Lys) variant of SLC40A1 (Ferroportin)
R167K (p.Arg167Lys) in SLC40A1 (Ferroportin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
R167K (p.Arg167Lys) variant details
- p.Arg167Lys
- rs750595460
- ExAC rs750595460
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- AlphaMissense 0.10
- MetaLR 0.69
- MetaSVM 0.26
- PolyPhen-2 0.67
- SIFT 0.48
- EVE 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available